COCACOLA and PEPSICOLA

Abstract Three of the most recognizable corporate names are Microsoft, a manufacturer of computer software, and Google and Yahoo, two internet search providers. Two of the most popular soft drink brand names are Coca-Cola and Pepsi-Cola. This article proposes to use the sequences of English alphabet letters in the names of these companies and products as the basis for creating five new peptides, MICROSOFT, GOOGLE, YAHOO, COCACOLA, and PEPSICOLA. This can be done by using a modified version of the International Union of Pure and Applied Chemistry’s one letter abbreviations for the names of amino acids. In this modification, the unassigned letter, O, is used to represent the amino acid, Ornithine. Precedent for this assignment already exists in the chemical literature. Ornithine does not occur in natural proteins, and, therefore, the letter, O, does not occur among the amino acid sequences of any protein database. However, Ornithine is structurally and chemically very similar to the amino acid, Lysine, which does occur in natural proteins and which is represented by the one letter abbreviation, K, in the IUPAC system. A search of the National Center for Biotechnology Information protein databases for the letter sequences, MICRKSKFT, GKKGLE, YAHKK, CKCACKLA and PEPSICKLA, where the one letter abbreviation, K, for Lysine, replaced the letter, O, returned numerous exact (GKKGLE and YAHKK) and partial (MICRKSKFT, CKCACKLA and PEPSICKLA) sequence matches. This result indicates that all of the search sequences are common in proteins. There are no synthetic barriers to the creation of these Ornithine containing peptides. Consequently, it is predicted that the synthetic peptides, MICROSOFT, GOOGLE, YAHOO, COCACOLA, and PEPSICOLA, will all exhibit biological activities.